Bedroom is the place where we start and end up the day every day and that is the reason that it becomes an important to keep it neat, clean, and organized. Clean Room is having similar kind of importance in Difference Industries which increase or improve their life and Quality. Clean Room is basically a Facility to keep atmosphere extremely healthy for Scientific research, Pharmaceutical Medicine Manufacturing, Electronic Parts like IC, CRT, LCD, OLED and Many more. We are designing Clean Room Considering the type of application and its importance in Human Being. For Example, in Pharmaceutical there are difference kind of Medicine which requires Difference Kind of Quality. Clean Room is one of the essential requirements in Research where Air Quality & Its contamination, Pressure and Temperature are an Important Parameters which we must control and keep under tolerance as per difference kind of region requirement. Doors and Its Hardware are one of the important items which we are keeping in mind for best Clean Room design. These must be required to purchase from quality supplier who understood the requirement and design accordingly.